AMBROTOSE TM.





Essential Information About The Eight Essential Saccharides
              
Q: What is AMBROTOSE?

A:   A patented complex of proprietary, standardized natural saccharides, AMBROTOSE is a unique nutritional supplement designed to provide the eight essential saccharides required by the body to produce correctly structured, optimally functioning glycoproteins.
 
Q: What are the functions of glycoproteins?

A:  Glycoproteins are a group of complex molecules found in plants, animals and microorganisms, and are made up of a sugar and a protein. Found on the surface of cells,  glycoprotein molecules play a key role in all cellular communication. To maintain a healthy body, cells must "talk" to other cells.  Just as words are made from letters of the alphabet,  DNA builds cellular "words" from biochemical "letters" called glycoproteins.  Molecular biologists refer to this cell-to-cell information exchange as "cell-cell communication." 

Q:  What happens when there is an inadequate supply of properly structured glycoproteins?

A:  Healthy bodies, comprised of many components working together in sophisticated harmony, must have accurate internal communication to function correctly.  Glycoproteins warn when disease is present, sending messages for help when the cells need it.  When the body operates from an insufficient supply of glycoproteins, or operates from a supply of improperly structured glycoproteins due to a lack of essential "building blocks," there is a major breakdown in this communication process. Research has implicated a wide range of disorders with glycoprotein abnormalities:  autoimmune disorders, such as rheumatoid arthritis and systemic lupus erythematosus;  Crohn's Disease; cancers; tuberculosis, in a partial list.

Q:  What do the essential saccharides have to do with this process?

A:  Harper's Biochemistry, a textbook published in 1996, by Murray, et al,  identifies eight monosaccharides commonly found in human glycoproteins which are known to be important to the healthy functioning of the human body. Coming from a universe of approximately 200 monosaccharides found in nature, the essential eight saccharides are: galactose, glucose, mannose, N-acetylneuraminic acid, fucose, N-acetylgalactosamine, N-acetylglucosamine, and xylose. If any of the required saccharide building blocks for glycoproteins are missing, or are in short supply, glycoprotein "letters" are not formed, or are altered, with the resultant shut down or faulty cellular communication.  The body experiences these garbled messages as various symptoms, or as degenerative or disease conditions.

Q:  Can you give me examples of the sorts of scientifically proven effects these essential saccharides have?

A:  The best way to do that is to quote from the United States patent granted on April 21, 1992 to the researchers who identified and stabilized the functional component of the aloe vera plant, a biologically active polysaccharide called a Beta- 1, 4 mannan molecule.  The nutritional form of this polysaccharide is called Manapol, one of the essential saccharides in AMBROTOSE.  The patent refers to administering the above mentioned sugar molecule to a mammal in an amount "sufficient to effect monocyte and macrophage [white blood cell] stimulation, resulting in medical benefits that include: modulation of the immune system; enhanced wound healing; vaccine systemic adjuvant effect [i.e., enhances the effectiveness of the vaccine]; general antiviral activity; malignant tumor and leukemic cell destruction; clinical improvement for patients with AIDS, colitis, multiple sclerosis, neuralgia, multiple bacterial and viral infections."

Q:  What materials does the body use to build these important glycoprotein molecules?

A:  Plants, which have captured the sun's energy to produce carbohydrates (sugars), are the primary building blocks for the saccharide portion of glycoprotein molecules.  The body breaks down plant carbohydrates, restructures them into small sugars, then uses those sugars to build glycoproteins.  Since up to 85% of glycoproteins are composed of 8 specific saccharides, the dietary need for these sugars is essential.  However, ordinary dietary sources provide only two of the essential sugars: glucose and galactose.  Glucose is supplied from such food sources as wheat, rice, and sugar cane.  Both glucose and galactose are supplied from milk, but lactose-intolerant individuals or others who do not eat dairy products lack even this saccharide, since galactose is derived from the lactose in milk.  The other six saccharides must either be synthesized by the body or obtained from dietary supplements. One of these essential saccharides has been available in supplement form as Mannatech's Manapol, derived from the renowned aloe vera plant. The phenomenal results Manapol users experienced from supplementing with just one essential saccharide was the stimulus for continued research,  leading to the development of a supplement which includes the complete eight essential saccharides.

Q:  Can you put all of this together for me?

A:  An absence or an insufficiency of essential saccharides leads to an absence or an insufficiency of glycoproteins, or to incorrectly structured glycoproteins, which causes a breakdown in cellular communications experienced as symptoms or disease.  Dietary sources provide only one or two essential sugars, making the need for nutritional supplementation clear.   AMBROTOSE and Man-Aloe are Mannatech's  patented nutritional formulations of the eight essential saccharides.  Only Mannatech can provide this unique saccharide complex.  Support your body's glycoproteins and cellular communication system.  Don't expect your body to perform on short supplies!

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